On 26 November 2025, the European Parliament and the Council adopted Regulation (EU) 2025/2455, formally establishing a Common Data Platform on Chemicals, which will take effect on 1 January 2026. The Regulation aims to transform chemical safety governance in the EU by unifying fragmented chemical data into a single system that is findable, accessible, interoperable, and reusable. The platform, primarily managed by the European Chemicals Agency (ECHA), will serve as a central evidence base by integrating data from nearly 70 EU chemical-related legislative acts. It will consolidate datasets provided by ECHA, the European Food Safety Authority (EFSA), the European Medicines Agency (EMA), the European Environment Agency (EEA), and other bodies. By 2 January 2029, the platform must include core datasets listed in Annex IV, such as REACH registrations, CLP inventories, biocides, drinking water data, food and environmental monitoring data, industrial and air emissions data, and medicinal product information. Older chemical datasets generated before 1 January 2026 will be progressively incorporated by 2 January 2036. The Regulation also introduces an Early Warning and Action System for emerging chemical risks, coordinated by the EEA, with the first annual report due by 2 July 2027. Additionally, it mandates study notifications, requiring businesses to inform ECHA of newly commissioned regulatory studies, and establishes a centralized database for these notifications by 2 November 2027. Furthermore, the platform strengthens human biomonitoring by requiring EU-wide data integration and the commissioning of a Union-wide human biomonitoring study by 2 January 2030.